The safety and effectiveness of this drug hasn’t been established in children. It shouldn’t be used in children younger than 18 years.Published animal data have reported increased neonatal mortality hinein the offspring of male rodents that were treated with methadone prior to mating. Rein these studies, the female rodents were not treated with

Methadone is contraindicated in patients with a known hypersensitivity to methadone hydrochloride or any other ingredient in methadone hydrochloride tablets.As with all opioid drugs, it is necessary to adjust the dosing regimen for each patient individually, taking into account the patient's prior analgesic treatment experience. The following dosin

“Drug-seeking” behavior is very common hinein addicts and drug abusers. Drug-seeking tactics include emergency calls or visits near the end of office hours, refusal to undergo appropriate examination, testing or referral, repeated claims of lost prescriptions, tampering with prescriptions and reluctance to provide prior medical records or conta